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Labs

Bioprocess Labs

NCTM offers a variety of well-equipped laboratory spaces for on-site training and applied research. Our four primary bioprocess labs are dedicated to cell culture, analytical methods, microbial fermentation, and downstream manufacturing with each lab housing a unique set of instruments designed to simulate every unit operation utilized in biomanufacturing facilities. Our skilled staff and stocked laboratories allow us to perform cutting-edge workforce development, process development and process scale-up to support the next generation of the biomanufacturing industry.

Equipment List

Cytiva Xcellerex 50 liter single use bioreactor

Cell Culture Suite

  • Cytiva Xcellerex XDR 50 single-use bioreactor (50L)
  • Labconco Class II, Type A2 biosafety cabinets
  • New Brunswick Galaxy® 170 S CO2 incubators
  • PBS Biotech PBS 3 MAG spinning wheel bioreactor
  • PBS Biotech PBS MINI spinning wheel bioreactor
  • Sartorius BIOSTAT® RM50
  • Sartorius BIOSTAT® CultiBag RM rocking motion bioreactor with RM20 and RM50 platforms
  • Eppendorf BioFlo® 320 bioreactor with 14L vessel
  • Nova Biomedical FLEX2 bioanalyzer and automated cell counter
  • Thermo Fisher CryoExtra™ 20 LN2 storage vessel
  • Invitrogen Neon® transfection system
  • Eppendorf 5810 R centrifuges
  • Bio-Rad TC20™ automated cell counters
  • Beckman Coulter ViCELL BLU automated cell counter
  • Eppendorf epMotion 5073 automated liquid handler with HEPA filter
  • Olympus IX53 inverted fluorescence microscope with camera
  • ZEISS Primo Vert inverted microscopes
  • Leica DM750 upright microscopes
  • Thermo Scientific Reach-In CO2 incubator
  • VWR® symphony™ CO2 incubators
Operators using the CIP (Clean in Place) system to clean a disc stack centrifuge between separation cycles

Microbial Fermentation and Recovery Suite

  • New Brunswick BioFlo® 610 stainless steel 125L bioreactor
  • Eppendorf BioFlo® 320 fermentors with 5L and 14L vessels
  • SaniMatic UltraFlo 45 CIP skid
  • Microfluidics M-110P homogenizer
  • GEA Lab Homogenizer Panther 3006
  • Beckman Coulter Avanti high speed floor centrifuges
  • GEA Westfalia Separator disc stack centrifuge
  • GEA WhisperFuge® Solid Bowl Clarifier
  • YSI 2900D biochemistry analyzer
  • Sartorius Biosealer® TC
  • Sarotius Biowelder® TC
  • New Brunswick Scientific I 24 Incubator Shaker Series
  • QSonica Q500 Sonicator
  • Panasonic MLS Series top-loading portable autoclave
  • STERIS® AMSCO® 250LS Autoclave
  • STERIS® AMSCO® 430LS Autoclave
Operators preparing for purification via chromatography using the AKTA Process system

Downstream Lab

  • Cytiva ÄKTA process™ chromatography system
  • GE ÄKTA Pilot chromatography systems
  • GE ÄKTA Avant 25 chromatography system
  • GE ÄKTA Avant 150 chromatography systems
  • GE ÄKTAmicro chromatography system
  • GE AxiChrom™ and BPG column housings
  • Precision Nanosystems NanoAssemblr® Ignite™ LNP encapsulation device
  • Millipore TF2S Mobius® FlexReady Solution for TFF
  • Spectrum Labs KrosFlo® Research IIi TFF systems
  • Spectrum Labs KrosFlo® MiniKros PILOT TFF system
  • Repligen KrosFlo® KR2i TFF System
  • Millipore Pellicon® TFF cassette and mini cassette assemblies
  • Watson Marlow 720U (66 LPM) peristaltic pump
  • Millipore Millistak+® Pod depth filter holder
  • Millipore Integritest® 4 filter integrity tester
  • Millipore Mobius® Power MIX 100 single-use mixer
  • 100L Stainless Steel mixer
  • Mettler Toledo PUA579 1000 lb. floor scale with ramp
  • Labconco FreeZone 2.5L lyophilizer
  • M&O Perry P-1540 vial filler
Operator retrieving a sample vial from the HPLC (High Performance Liquid Chromatography) system

Analytical Lab

  • Dionex UltiMate® 3000 HPLC system with PDA and charged aerosol device detectors
  • BioTek® Synergy™ H1 multi-mode plate reader
  • BioTek® ELx50 ELISA plate washer
  • Bio-Rad ChemiDoc™ MP gel and western blot imaging system
  • Forté BIO BLItz® Label-Free Protein Analysis System
  • GE SimpliNano™ spectrophotometer
  • GE Sievers 900 Laboratory TOC analyzer with auto sampler
  • Promega Spectrum Compact CE (Capillary Electrophoresis) System
  • Applied Biosystems 7500 Fast Real-time PCR system
  • Bio-Rad QX200™ Droplet Generator and Droplet Reader
  • Bio-Rad PX1™ PCR Plate Sealer
  • Bio-Rad C1000 Touch™ thermal cycler
  • Bio-Rad T100™ thermal cycler
  • Beckman Coulter DU® 730 UV-VIS spectrophotometer
  • Malvern Zetasizer Pro
  • Lighthouse Worldwide Solutions Solair 3100 airborne particle counters
  • Millipore MAS-100 Eco® air samplers
  • Thermo Scientific Genesys 10S UV-VIS spectrophotometers
  • Mettler Toledo Seven Compact conductivity meters
  • Thermo Scientific Orion Dual Star pH meters
  • Elga PureLab Ultra pure water system
  • New Brunswick Ultra-Low Temperature Freezer
  • Bio-Rad Trans-Blot® Turbo™ Transfer Systems
  • Bio-Rad Mini-PROTEAN® Tetra Systems
  • Bio-Rad Mini-Sub® cell GT

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